Nemus Bioscience Reports Prodrug of Tetrahydrocannabinol (THC) Issued Patent Coverage in Canada and Hong Kong

8 months ago

COSTA MESA, CA–(Marketwired – May 17, 2017)NEMUS Bioscience, Inc. ( OTCQB : NMUS ) announced that patents have been granted in Canada and Hong Kong covering the company’s proprietary prodrug of THC, THC-valine-hemisuccinate (THCVHS), as well as other amide-ester forms of cannabinoid-based molecules. These patents are licensed to Nemus by the University of Mississippi, and further broaden the potential commercial territories for THCVHS. The molecule has already received patent coverage in the United States, Japan, the United Kingdom, the European Union, and Australia. THCVHS is the active pharmaceutical ingredient (API) in Nemus’ glaucoma drug candidate known as NB1111.

“Nemus is very pleased with the patent coverage of this proprietary, bio-engineered version of THC, especially in the Asian markets of Hong Kong and Japan. While glaucoma in western economies is often associated with elevated intra-ocular pressure (IOP), the majority of Asian patients suffer from normo-tensive glaucoma marked by death of the optic nerve in the setting of normal IOP. For these patients, having a therapy with neuroprotective capability, like the cannabinoid-class of molecules, might prove to be a potential first-line therapy,” commented Brian Murphy, M.D., CEO and Chief Medical Officer of Nemus. “Our goal is to complete the formulation stage of eye drop development in anticipation of human proof-of-concept studies that can deliver a more hydrophilic or water soluble form of THC into multiple compartments of the eye. In addition, we plan to move forward the suppository formulation of THCVHS for the management of chemotherapy-induced nausea and vomiting (CINV).”

Dr. Mahmoud ElSohly, professor at the National Center for Natural Products Research (NCNPR) at the University of Mississippi commented: “The University is gratified to have years of innovative research recognized by a diverse number of territories globally. We look forward to continuing our relationship with Nemus to grow the patent estate not only related to the prodrug of THC and the analogue of CBD, but other types of cannabinoids as well.”

Dr. Murphy noted, “The recently signed Series E financing led by Schneider Brothers Ltd is a transformative event for Nemus. We look forward to advancing pipeline leads into first-in-human studies as well as working to partner our precision-based cannabinoid therapy where drug delivery is tailored to specific medical conditions in eastern as well as western commercial markets.”

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