Protagenic Therapeutics (PTIX) is a New York-based biotechnology company developing a platform of first-in-class treatments for stress-related disorders like PTSD, depression, anxiety, and drug & alcohol addiction. These disorders are growing in prevalence, and are lacking safe, effective treatments for millions of sufferers globally. For decades, scientists and clinicians have documented the association with and impact of stress in these disease states (see “Stress Feedback Loop”). Protagenic’s lead compound (PT00114) taps into a brain system that counteracts stress overdrive at a cellular level in the brain, helping break the vicious cycle of stress leading to psychological and physical harm and further sensitivity to stress.